Congenital alopecia

Congenital alopecia refers to a condition where an individual is born with little to no hair. This can range from complete baldness (including eyebrows and eyelashes) to patchy areas of hair loss. There are several underlying causes, each with varying degrees of severity and treatment options.

* Genetic disorders: Mutations in genes responsible for hair follicle development can cause congenital alopecia. Examples include Atrichia with Papular Lesions (APL) and Hypotrichosis simplex.
* Syndromic conditions: Congenital alopecia can be a symptom of a broader syndrome affecting multiple body systems. Examples include T-cell immunodeficiency, congenital alopecia, and nail dystrophy (TCAN) and Aplasia cutis congenita.

Diagnosis typically involves a physical examination of the scalp and hair, along with a detailed medical history. In some cases, genetic testing or a scalp biopsy may be needed to pinpoint the specific cause.

Unfortunately, there’s no cure for most forms of congenital alopecia. However, treatment options may focus on:
Hair replacement: Wigs, hairpieces, or scalp micropigmentation (a cosmetic tattoo technique) can offer cosmetic solutions.
Addressing underlying conditions: If congenital alopecia is part of a syndrome, treating the underlying condition may improve hair growth.

Disclaimer: This information is for educational purposes only and should not be interpreted as medical advice. Please consult a healthcare professional for diagnosis and treatment of congenital alopecia.